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About Novelwise

Pharmaceutical is a biopharmaceutical company dedicated to the discovery and development of a series of histone deacetylase (HDAC) inhibitor programs for oncology and other diseases with high unmet medical needs.

Zhong Yang Huang, Ph.D

Chairman of the Board

Keith Chan, Ph.D

Chief Executive Officer

Tai-Sen Soong, Ph.D

Special Advisor to the Chairman

Metastatic Uveal Melanoma

Mutations in the BAP1 gene prevent normal protection of p53, a key tumor suppressor. At the same time, overexpression of HDAC8 blocks the transcription of p53 protein, allowing cancer cells to grow unchecked. NBM-BMX is a selective HDAC8 inhibitor designed to restore this critical pathway.

Glioblastoma

Glioblastoma

Mutations in the BAP1 gene prevent normal protection of p53, a key tumor suppressor. At the same time, overexpression of HDAC8 blocks the transcription of p53 protein, allowing cancer cells to grow unchecked. NBM-BMX is a selective HDAC8 inhibitor designed to restore this critical pathway.

Investigator-Initiated Trial

Investigator-Initiated Trial

Hepatocellular Carcinoma:Investigator-Initiated Trial

Mesothelioma:Investigator-Initiated Trial

Clear Market Focus

Advancing a lead program in uveal melanoma (UM) with liver metastasis.

Innovative Pipeline

Expansion to novel HDAC8 and other selective HDAC compounds.

Strategic Collaborations

Engaging with leading CROs, academic centers, and patient advocacy groups.